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2 edition of Bioassay of o-anisidine hydrochloride for possible carcinogenicity. found in the catalog.

Bioassay of o-anisidine hydrochloride for possible carcinogenicity.

National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.

Bioassay of o-anisidine hydrochloride for possible carcinogenicity.

by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention.

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  • 24 Currently reading

Published by Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Cancer Institute, Division of Cancer Cause and Prevention, Carcinogenesis Testing Program in Bethesda, Md .
Written in English

    Subjects:
  • Carcinogens.,
  • Dyes and dyeing -- Toxicology.,
  • Amines -- Toxicology.

  • Edition Notes

    SeriesDHEW publication -- no. (NIH) 78-1339, Carcinogenesis technical report series -- no. 89
    The Physical Object
    Pagination140 p. in various pagings :
    Number of Pages140
    ID Numbers
    Open LibraryOL22412255M

    NCI (a) Bioassay of 4-chloro-o-phenylenediamine for possible carcinogenicity, NCI Tech. Rpt Series No. NCI (b) Bioassay of o-anisidine hydrochloride for possible carcinogenicity, NCI Tech. Rpt Series No. NCI (c) Bioassay of aniline hydrochloride for possible carcinogenicity, NCI Tech. Rpt Series No. NCI (a).Cited by:   o-Anisidine is used chiefly in the manufacture of dyes, one method being the diazotization of o-anisidine and coupling with other aromatic amines or phenols to yield a large number of the azo dyes. A bioassay of o-anisidine hydrochloride for possible carcinogenicity was conducted by administering the test chemical in feed to Fischer rats and B6C3F1 mice.

    The mechanism of DNA damage by a metabolite of the carcinogen o-anisidine in the presence of metals was investigated by the DNA sequencing technique using 32P-labeled human DNA fragments. The o-anisidine metabolite, o-aminophenol, caused DNA damage in the presence of Cu(II). A bioassay of 5-nitro-o-anisidine for possible carcinogenicity was conducted using Fischer rats and B6C3F1 mice. /The cmpd/ was administered in the feed, at either of two concentrations, to groups of 50 male and 50 female animals of each species.

    o-Anisidine is a dangerous pollutant from the production of dyes. It is listed as RCRA hazardous waste, with the code K [6] The International Agency for Research on Cancer (IARC) has classified o -anisidine as a Group 2B, possible human al formula: C₇H₉NO. NIH Publ No 77– () Bioassay of nitrilotriacetic acid and nitrilotriacetic acid, trisodium salt, monohydrate for possible carcinogenicity. Natl Cancer Inst, Bethesda, Maryland Google Scholar NIH Publ No 78– () Bioassay of o-anisidine hydrochloride for possible by: 1.


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Bioassay of o-anisidine hydrochloride for possible carcinogenicity by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention. Download PDF EPUB FB2

BIOASSAY OF. o-ANISIDINE HYDROCHLORIDE. FOR POSSIBLE CARCINOGENICITY. Carcinogenesis Testing Program. Division of Cancer. Cause and Prevention National Cancer Institute National Institutes of Health Bethesda, Maryland U.S.

DEPARTMEN OTF HEALTH, EDUCATION, AN D WELFARE Public Health Service National Institute osf Health. DHEW Publicatio. Get this from a library. Bioassay of o-anisidine hydrochloride for possible carcinogenicity. [National Cancer Institute (U.S.).

Division of Cancer Cause and Prevention.]. EPA has not classified o-anisidine for carcinogenicity. IARC has classified o-anisidine as a Group 2B, possible human carcinogen. (5) Physical Properties A common synonym for o-anisidine is ortho-anisidine. (1) o-Anisidine is a yellowish-liquid that is slightly soluble in water.

(1) The chemical formula for o-anisidine is C 7 H 9. Bioassay of o-anisidine hydrochloride for possible carcinogenicity. Bethesda, Md.: Dept. of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Cancer Institute, Division of Cancer Cause and Prevention, Carcinogenesis Testing Program.

A bioassay of o-toluidine hydrochloride for possible carcinogenicity was conducted by administering the test chemical in feed to F rats and B6C3F1 mice.

Groups of 50 rats of each sex and 50 mice of each sex were administered o-toluidine hydrochloride at one of several doses, either 3, or 6, ppm for rats and either 1, or 3, ppm for the mice, for to weeks.

A bioassay of o-anisidine hydrochloride for possible carcinogenicity was conducted by administering the test chemical in feed to Fischer rats and B6C3F1 : National Toxicology Program. o-Anisidine hydrochloride: Target Organs and Levels of Evidence for TR Bioassay of o-Anisidine Hydrochloride for Possible Carcinogenicity (CASRN ).

o-Anisidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity in experimental animals. Cancer Studies in Experimental Animals.

Oral exposure to o-anisidine administered as its hydrochloride salt caused tumors in two rodent species and at two different tissue Size: KB. Bioassay of o-Anisidine Hydrochloride for Possible Carcinogenicity (CASRN ) Technical Report: TR PDF (3MB) Bioassay of Fenthion for Possible Carcinogenicity (CASRN ) Technical Report: GMM PDF (2MB).

The potential of o-nitrotoluene and p-nitrotoluene to cause cancer in mammalian species was studied in male and National Cancer Institute, a. Bioassay of o-anisidine hydrochloride for possible carcinogenicity.

Ser. Bioassay of o-toluidine hydrochloride for possible carcinogenicity. DHEW Publication. Google Scholar. Cited by: A bioassay of 3,3'-iminobispropanol dimethanesulfonate (ester) hydrochloride [IPD] for possible carcinogenicity was conducted by administering the test chemical intraperitoneally to Sprague-Dawley rats and B6C3F1 mice.

The IPD was injected three times per week to groups of 35 animals, using doses of 12, 24, or 48 mg/kg for the rats, and 20 or 40 mg/kg for the mice. Bioassay of p-anisidine hydrochloride for possible carcinogenicity (OCoLC) Material Type: Government publication, National government publication: Document Type: Book: All Authors / Contributors: National Cancer Institute (U.S.).

Division of Cancer Cause and Prevention.; Carcinogenesis Testing Program (U.S.); National Institutes of Health (U.S.). Comparative carcinogenicity of o -toluidine hydrochloride and o -nitrosotoluene in F rats ☆ This publication is dedicated to the founder of the American Health Foundation, Dr.

Ernst L. Wynder, on the occasion of the 10th anniversary of the Naylor Dana Institute for Disease by: Bioassay of p-anisidine hydrochloride for possible carcinogenicity (OCoLC) Material Type: Document, Government publication, National government publication, Internet resource: Document Type: Internet Resource, Computer File: All Authors / Contributors: National Cancer Institute (U.S.).

Division of Cancer Cause and Prevention. Bioassay of phenazopyridine hydrochloride for possible carcinogenicity Item Preview remove-circle Share or Embed This Item.

Bioassay of phenazopyridine hydrochloride for possible carcinogenicity by National Cancer Institute (U.S.). Division of Cancer Cause and Prevention. Bioassay of o-toluidine hydrochloride for possible carcinogenicity (OCoLC) Material Type: Government publication, National government publication: Document Type: Book: All Authors / Contributors: National Cancer Institute (U.S.).

Division of Cancer Cause and Prevention.; Carcinogenesis Testing Program (U.S.); Frederick Cancer Research. Enhanced mutagenicity of anisidine isomers in bacterial strains containing elevated N-acetyltransferase activity.

Bioassay of o-anisidine hydrochloride for possible carcinogenicity. National Cancer Institute, Technical Report No. 89 () Google Scholar. by: NTP. o-Anisidine hydrochloride ().

Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP). Accessed Genotoxic mechanisms for the carcinogenicity of the environmental pollutants and carcinogens o-anisidine and 2-nitroanisole follow from adducts generated by their metabolite N-(2-methoxyphenyl)-hydroxylamine with deoxyguanosine in DNA.

Correspondence address: Prof. Marie Stiborová, by: 4. Search for books, ebooks, and physical Bioassay of phenoxybenzamine hydrochloride for possible carcinogenicity Published: () Bioassay of ICRF for possible carcinogenicity Published: () Bioassay of sulfisoxazole for possible carcinogenicity Published: (.

Bioassay of piperonyl butoxide for possible carcinogenicity Published: () Bioassays of DDT, TDE, and p, p'-DDE for possible carcinogenicity Published: () Bioassay of dixathion for possible carcinogenicity Published: ().Redox cycling in the metabolism of the environmental pollutant and suspected human carcinogen o-anisidine by rat and rabbit hepatic microsomes.

Chem Res Toxicol NTP. (). Bioassay of o-anisidine hydrochloride for possible carcinogenicity.1. Author(s): Mason Research Institute.; National Institutes of Health (U.S.); Carcinogenesis Testing Program (U.S.) Title(s): Bioassay of o-anisidine hydrochloride for possible carcinogenicity.